by Kristen Monaco: For Complete Post, Click Here…
ngd-This is a fairly big deal, since NMDA receptor antagonists don’t work like any of the traditional anti-depressants. Still need real world studies on effectiveness. Both Dextromethorphan and buprion are availalbe separately for a variety of purposes…
Dextromethorphan-bupropion (Auvelity) tablets approved for MDD.
he FDA approved combination dextromethorphan and bupropion extended-release tablets (Auvelity) for adults with major depressive disorder (MDD), Axsome Therapeutics announced on Friday.
Dextromethorphan-bupropion is an oral N-methyl D-aspartate (NMDA) receptor antagonist, and “represents the first new oral non-monoamine-based mechanism of action approved to treat major depressive disorder in over sixty years,” Maurizio Fava, MD, of Massachusetts General Hospital in Boston, said in a statement from the drugmaker.
