Marine Omega-3 Fatty Acid Supplementation for Borderline Personality Disorder: A Meta-Analysis

By Dominika M. Karaszewska, BS; Theo Ingenhoven, MD, PhD; and Roel J. T. Mocking, MD, PhD.: For Entire Post, Click Here…

Objective: Several promising studies investigated marine omega-3 fatty acids (ie, fish oil) in borderline personality disorder (BPD), but overall effects remain unclear. The aim of this study was to obtain estimates of effectiveness of omega-3 fatty acids in BPD using meta-analysis, with a priori differentiation of affective, impulsive, and cognitive-perceptual symptom domains.

Conclusions: Available data indicate that marine omega-3 fatty acids improve symptoms of BPD, particularly impulsive behavioral dyscontrol and affective dysregulation. Marine omega-3 fatty acids could be considered as add-on therapy.

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