Risk of Substance Use Disorder and Its Associations With Comorbidities and Psychotropic Agents in Patients With Autism

By Jing-Syuan Huang; Fu-Chi Yang; Wu-Chien Chien; et al.: For Complete Post, Click Here…

ngd- Substance Use Disorder is also an issue for people with IDD, but is relatively untreated…

Key Points

Question  Do patients with autism have a higher risk of substance use disorder than the general population, and is this risk associated with psychotropic treatment, comorbidities, or mortality?

Findings  In this cohort study of 6599 individuals with autism spectrum disorder (ASD) and 26 396 controls without ASD, a diagnosis of autism was associated with an increased risk of substance use disorder, and the risk was much higher in those who had behavioral comorbidities and those who did not receive psychotropic agents. The mortality risk was higher in patients with autism and co-occurring substance use disorder than in non-ASD controls with or without substance use disorder.

Meaning  These findings suggest that patients with ASD are vulnerable to the development of substance use disorder, and the use of psychotropic agents for autism is associated with a decreased risk of substance use disorder.

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