Antibiotics in Infancy Tied to Later Allergic Illness

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Multiple classes of antibiotics upped risk, especially for asthma, allergic rhinitis.

Commonly prescribed antibiotics in infants were linked with higher risk of those children developing allergic diseases, such as asthma and allergic rhinitis, researchers found.

Infants prescribed penicillin, cephalosporin, and macrolide antibiotics showed higher rates of later diagnosis with allergic disease, reported Sidney Zven, BSCE, of the Uniformed Services University of the Health Sciences in Bethesda, Maryland, and colleagues in a research letter in JAMA Pediatrics.

Antibiotics adversely affect the microbiome “by decreasing bacterial diversity,” Zven and colleagues noted, which has been linked to allergic disease.

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