New food supplement made from bacteria fights metabolic syndrome

By Ana Sandoiu: For More Info, Go Here…

Scientists have now confirmed what they previously tested in mice: the benefits of a bacterium for cardiometabolic health. In a new study, a food supplement containing Akkermansia muciniphila improved metabolic markers in people with prediabetes and at risk of cardiovascular conditions.

The term “metabolic syndrome” describes a cluster of health risk factors, including obesityaround the waist, insulin resistancehigh blood pressure, and dyslipidemia, which refers to high total cholesterol levels or high levels of “bad” cholesterol.

Together, these risk factors may compromise a person’s cardiometabolic health, putting people at risk of cardiovascular disease and type 2 diabetes.

In fact, estimates show that having metabolic syndrome raises the risk of type 2 diabetes by fivefold and the risk of cardiovascular disease by threefold. Furthermore, studies have found links between metabolic syndrome and various forms of cancer, such as “breast, pancreatic, colon, and liver cancer.”

A. muciniphila improve metabolic health

The researchers aimed primarily to assess the safety and tolerability of the supplement, as well as its impact on metabolic parameters, such as insulin resistance, circulating lipids, fat around the waistline, and body mass.

A. muciniphila bacteria, either live or pasteurized for [3] months, was safe and well tolerated,” concluded the study. Importantly, people who took the pasteurized bacteria showed improvements in insulin sensitivity and lower cholesterol levels, along with slight reductions in body weight, fat mass, hip circumference, and markers of inflammation in the liver.

By contrast, the markers of metabolic health continued to deteriorate in people who took the placebo. Prof. Cani and the team conclude:

[This pilot study] shows that the intervention was safe and well tolerated and that supplementation with A. muciniphila improves several metabolic parameters.”

The research, which was a proof-of-concept study, shows that administering pasteurized Akkermansia to humans as a dietary supplement reduces cardiometabolic risk factors.

Leave a Reply