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Know the top ten
These Rx medications are among the most commonly prescribed drugs that can cause depression in adults, according to the JAMA study.
- Beta-blockers to treat high blood pressure such as metoprolol, atenolol, enalapril, and quinapril.
- Anti-anxiety medications such as alprazolam (Xanax and generic), clonazepam (Klonopin and generic), diazepam (Valium and generic) and lorazepam (Ativan and generic) as well as the sedative zolpidem (Ambien and generic).
- Opioids such as hydrocodone (Norco, Vicodin, Lorcet and generic), tramadol (Ultram, ConZip and generic).
- Corticosteroids such as cortisone, hydrocortisone or prednisone, which are used to treat a variety of conditions including asthma, lupus and rashes.
- Over-the-counter proton pump inhibitors omeprazole (Prilosec, Zegerid and generic) and esomeprazole (Nexium and generic) as well as over-the-counter antacids ranitidine (Zantac and generic) and famotidine (Pepcid and generic).
- Certain allergy and asthma medications. The over-the-counter allergy medication cetirizine (Zyrtec and generic) has been linked to depression, as has another type of drug, montelukast (Singulair), which is often used to treat people with allergic asthma.
- Anticonvulsant medications such as gabapentin (Neurontin and generic) and topiramate (Topamax and generic).
- Amitriptyline to treat nerve pain and prevent migraine headaches.
- Hormonal drugs. Estradiol (Delestrogen, Elestrin, EstroGel and generic), commonly used to treat menopausal symptoms and finasteride (Proscar, Propecia and generic), a medication used to treat an enlarged prostate and/or hair loss in men.